What is the recommended long-term storage condition for DNA extracts if they are in liquid form?

The recommended long-term storage condition for DNA extracts in liquid form is to keep them frozen. This method is optimal because it effectively preserves the integrity and stability of the DNA, preventing degradation over time. Freezing at temperatures typically around -20°C to -80°C minimizes enzymatic activity and inhibits microbial growth, which could otherwise compromise the sample.

Liquid DNA can be particularly susceptible to degradation at higher temperatures, where nucleases might remain active. By keeping the DNA frozen, the molecular structure remains intact, ensuring that it can be reliably analyzed in the future for forensic purposes or scientific research. This is a well-established practice in laboratories handling DNA, as it ensures that samples are maintained in a state that is conducive to long-term preservation.